Tuesday 20 September 2011

Hyperdense thalami : Perinatal ischemia

A 6 yo male with delayed milestone. Preterm hospital delivery. Not cried immediately after birth, was in NICU for 3months. 

CT Brain salient features:
  • Hyperdense thalami.
  • Cortical atrophy.
  • Ex vacuo dilatation of lateral ventricle with undulating walls suggestive of Gliosis and paucity of periventricular white matter - Periventricular leukomalacia.
Imaging findings and history supports Profund perinatal ischemia.

DDs of hyperdense thalami:
GM Gangliosidosis.
Profund perinatal ischemia.

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