Friday 9 September 2011

Corpus Callosal Complete Agenesis

CT Brain axial sections, MRI Brain Sagittal T1 and Coronal T1w images

Mid Sagittal T1w image of normal for comparison
Imaging findings in complete CC Agenesis:  
1. Parallel non converging widely separated lateral ventricles on axial sections,the most striking feature.
2. Occipital horn dilated – Colpocephaly.
3. Pointed or trident shaped frontal horns.
4. Non visualisation of normal stripe of CC on mid sagittal sections, gyri and sulci directly radiating from roof of third ventricle. 
5. High riding third ventricle. 
6. Absent cingulate gyrus which is normally seen parallel and cranial to CC.
7. Vertically originated hippocampi with key hole appearance of temporal horns on coronal sections.
8. Probst bundles, the abnormal longitudinally orientated band of white matter track medial to lateral ventricles seen on coronal sections.
9. May seen an associated lipoma or inter hemispheric cyst if any.

Agenesis of CC may be complete (all segment of CC absent) or Partial (usually body remains rest of the CC may be absent)

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