Thursday, 16 February 2012

Focal Cortical Dysplasia MRI

Left side inferior frontal gyrus is thick with poor grey white matter inter phase, convolution pattern is asymmetric compared to opposite side - a subtle and subjective finding of Focal Cortical Dysplasia.

Focal Cortical Dysplasia:
First described in 1971 by Taylor.
A congenital abnormality thought to be secondary to genetic, ischemic, toxic, or infectious insult during cortical development.
A distinct subtype of malformation of cortical development, neurons in corresponding area are larger than normal called balloon cells for their large elliptical shape, displaced nucleus, and lack of dendrites or axons. Often found near the cerebral cortex.
This area causes the signals sent through the neurons to misfire and contributes in seizure activity.
The common cause of intractable epilepsy in children and is a frequent cause of epilepsy in adults.

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