Sunday 12 February 2012

Multiple System Atrophy MRI

Axial T2 images at the level of Pons show a cruciform hyperintensity so called "hot cross bun" sign. An associated atrophy confined to brain stem and cerebellum. 

Diagnostic criterias for multiple system atrophy (MSA) includes : 
1st Autonomic failure/urinary dysfunction, 2nd Parkinsonism 3rd Cerebellar ataxia and 4th corticospinal dysfunction. 
Definitive diagnosis of MSA requires pathological confirmation.

The so-called "hot cross bun sign" is specific for MSA but not pathognomonic for MSA.

1 comment:

Anonymous said...

great sirji by dr vyanktesh