Corpus callosal Lipoma

Axial non contrast CT study brain shows a fat density along inter hemispheric fissure.
The mid line sagittal T1w image show a curvilinear type of lipoma along corpus callosum.
Role of MRI in this case is to rule out any associated Corpus callosal anamoly.
Corpus callosum is normal.

Related post :
Corpus-callosal-agenesis-with-lipoma
Meckel's Cave Lipoma
Lipoma at incisura

Intracranial lipoma 


Syn : Lipomatous hamartomas, as normally fat not present in CNS.
A congenital malformation , not true neoplasm.
Contributes < 0.5% of all intracranial tumors.
A focal fat density (dark 'z' black) on CT or fat signal intensity (white on T1w image) and is often out standing in the background of adjacent normal grayish brain parenchyma.
Noted as an isolated incidental finding or as part of an associated anomalies. Most common anomaly associated is Corpus callosal agenesis or dysgenesis.

Most common location is supra tentorium ~80%. In that most common location is mid line along corpus callosum ~ 50%, Suprasellar cistern attached to infundibulum, hypothalamus ~ 20%,  Pineal region ~15%. Meckel's cave and lateral fissures are rare locations.
Infra tentorium contributes remaining 20%, in that common locations are Cp angles, jugular foramen and foramen magnum.

Two types of intracranial lipoma:
1. Curvilinear type is a thin stripe along CC.
2. Tubulonodular type is a bulky nodular mass, frequently show dense nodular calcifications, and often associated with Corpus callosal or adjacent parenchymal anomalies.

Intracranial lipoma

MRI Brain Axial T1, T2 and FLAIR. 

This MRI study of brain shows:
A focal extra axial fat in the groove between Pons and right cerebellar hemisphere, follow same signal as that of sub cutaneous fat on MRI, hyper intense on T1 as well as T2w and FLAIR images.
T1 bright tissue or lesions are very few for example fat and Meth Hb ' a sub acute stage blood degradation product'.

In such situation low 'fat' density on CT is very definitive of Lipoma.

Intracranial lipoma 


Syn : Lipomatous hamartomas, as normally fat not present in CNS.
A congenital malformation , not true neoplasm.
Contributes < 0.5% of all intracranial tumors.
A focal fat density (dark 'z' black) on CT or fat signal intensity (white on T1w image) and is often out standing in the background of adjacent normal grayish brain parenchyma.
Noted as an isolated incidental finding or as part of an associated anomalies. Most common anomaly associated is Corpus callosal agenesis or dysgenesis.

Most common location is supra tentorium ~80%. In that most common location is mid line along corpus callosum ~ 50%, Suprasellar cistern attached to infundibulum, hypothalamus ~ 20%,  Pineal region ~15%. Meckel's cave and lateral fissures are rare locations.
Infra tentorium contributes remaining 20%, in that common locations are Cp angles, jugular foramen and foramen magnum.

Two types of intracranial lipoma:
1. Curvilinear type is a thin stripe along CC.
2. Tubulonodular type is a bulky nodular mass, frequently show dense nodular calcifications, and often associated with Corpus callosal or adjacent parenchymal anomalies.

Related posts:
Lipoma along Trigeminal nerve
Lipoma at incisura
Lipoma along normal Corpus callosum
Lipoma with Corpus callosal malformation

Reference : Anne G Osborn 

Corpus callosal Agenesis with Lipoma

Non contrast CT Brain, MRI Brain Axial T1 and Sagittal T1w images

Findings are non converging, widely separated parallel lateral ventricles due to Corpus Callosal partial Agenesis better seen on MRI sagittal T1w images as splenium portion of CC is not visualized (white arrow)
There is an associated inter hemispheric lipoma with curvilinear calcification.

Related post :
Corpus-callosal-lipoma 
Meckel's Cave lipoma
Lipoma at incisura

Intracranial lipoma 

Syn : Lipomatous hamartomas, as normally fat not present in CNS.
A congenital malformation , not a true neoplasm.
Contributes < 0.5% of all intracranial tumors.

A focal fat density (dark 'z' black) on CT or fat signal intensity (white on T1w image) and is often out standing in the background of adjacent normal dark brain parenchyma on T1w images.
Noted as an isolated incidental finding or associated with other anomalies as a part of syndrome. Most common anomaly associated is Corpus callosal Agenesis / Dysgenesis.

Most common location is supra tentorium ~80%. In that most common location is mid line along corpus callosum ~ 50%, Suprasellar cistern attached to infundibulum, hypothalamus ~ 20%,  Pineal region ~15%. Meckel's cave and lateral fissures are rare locations.
Infra tentorium contributes remaining 20%, in that common locations are Cp angles, jugular foramen and foramen magnum.

Two types of intracranial lipoma:
1. Curvilinear type is a thin stripe along CC.
2. Tubulonodular type is a bulky nodular mass, frequently show dense nodular calcifications, and often associated with Corpus callosal or adjacent parenchymal anomalies.

MRI can't replace CT completely.

A 72 yo male comes for MRI Brain and Angiography (Stroke protocol) with history of recent onset giddiness.
In this case I’m just sharing my experience, what mistake we can do on MRI console when we get influenced by history or the clinical situation.
Let's go thro' the MRI brain images and the MR Angiography which is subjected to me as an emergency. In stroke protocol as an emergency we perform limited sequences. Flair 1st  followed by Diffusion, T2*GRE and MR Angio of brain neck at the end.

Axial FLAIR images show a focal hyperintensity in left half of ambient cistern near tentorium.
Lesion shows low signals on T2*GRE.
Diffusion is non contributory.
Lesion is very close or along the course of left PCA, picks up flow on non contrast MRI Angio which is subjected to me by my technician.
Can u guess what can it be. Ok ill tell what i was thinking - A left PCA cortical branch aneurysm with bleed on GRE.
I asked for T1 and T2 images for confirmation.

The tissue is bright on T1 and hyperintense to T2. Again hematoma or blood clot in an aneurysm possible as meth Hb a sub acute stage blood degradation product is bright on T1. On T2w images there is some distortion of normal pattern of cerebellar folia near cranial portion of cerebellum can be attributed an associated focal Gliosis. So side by side my report was also getting ready mentioning these findings.
What u say?
But somehow i was not very convinced.
I requested for CT sections. Just imagine running so many sequences in an emergency may start irritating people around u particularly your technicians. But never mind.
Now see CT sections...

It’s a typical fat density tissue, the lipoma giving bright signals on T1, high signals on T2 and FLAIR. Low signal on T2*GRE which is unexpected in lipoma that confused me, but is due to para magnetic effect of nodular calcifications around the lipoma which is known. Distortion of cranial portion of cerebellar folia is an associated malformation of superior cerebellar vermis. Picks up flow related signal when u do add vessel on Angio is artifactual.

So please don’t get influenced with history and clinical situation.
Really MR can't replace CT completely.


Imaging diagnosis : Lipoma at incisura with calcification.

Related posts:
Corpus-callosal-lipoma
Corpus-callosal-agenesis-with-lipoma
Lipoma lateral to pons
Meckel's cave Lipoma


Intracranial lipoma 

Syn : Lipomatous hamartomas, as normally fat not present in CNS.
A congenital malformation , not true neoplasm.
Contributes < 0.5% of all intracranial tumors.
A focal fat density (dark 'z' black) on CT or fat signal intensity (white on T1w image) and is often out standing in the background of adjacent normal grayish brain parenchyma.
Noted as an isolated incidental finding or as part of an associated anomalies. Most common anomaly associated is Corpus callosal agenesis or dysgenesis.

Most common location is supra tentorium ~80%. In that most common location is mid line along corpus callosum ~ 50%, Suprasellar cistern attached to infundibulum, hypothalamus ~ 20%,  Pineal region ~15%. Meckel's cave and lateral fissures are rare locations.
Infra tentorium contributes remaining 20%, in that common locations are Cp angles, jugular foramen and foramen magnum.

Two types of intracranial lipoma:
1. Curvilinear type is a thin stripe along CC.
2. Tubulonodular type is a bulky nodular mass, frequently show dense nodular calcifications, and often associated with Corpus callosal or adjacent parenchymal anomalies.